Map O'Duffy's Pub 804 W Vine St, Kalamazoo, MI 49001 Add To Trip WebsitePhone: (269) 381-9771 Description A place to meet friends, both old and new, share stories, all without the distraction of television. Non smoking since it's opening in 1999. Serving Gold Standard Award Guinness every time! Cosmo's Cucina is located upstairs of O'Duffy's. Videos TripAdvisor® Traveler Reviews More To Explore Categories: Restaurants Eat & Drink City: Kalamazoo Region: Southwest Although the MEDC uses reasonable efforts to maintain the accuracy of the website content, it is not represented to be error free. Read legal information.